What is your systemic therapy approach to women with isolated local recurrences of hormone-receptor positive breast cancer?

Topics: Breast Cancer • Medical Oncology • NCI-CCC Tumor Board Question • Yale

How does the timing of recurrence play into your decision?

Answer from: Medical Oncologist at Academic Institution

I will assume this case involves a chest wall or other local recurrence. In this case, it depends on whether the tumor is resectable. Based on the CALOR trial, wide resection, XRT (if not previously done), and anti-hormonal therapy would be the way to go. I would probably try to add a CDK4/6 inhibit...

Comments

Medical Oncologist at Christie NHS Foundation Trust
A chest wall recurrence after mastectomy is more w...

Medical Oncologist at Ralph Lauren Center for Cancer Care and Prevention
I have a similar case of a patient who opted for n...

Medical Oncologist at University of Pittsburgh School of Medicine
You would not be faulted for giving chemo given th...

Medical Oncologist at Ralph Lauren Center for Cancer Care and Prevention
Thank you for your quick reply! Very helpful!

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