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What is your therapy of choice for relapsed metastatic alveolar rhabdomyosarcoma?

If you had to recommend two options, one of which was palliation, what would your second option be?
1 Answer
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Pediatric Hematology/Oncology · Children's Mercy Hospitals and Clinics
Answered on

I will make just a couple of presumptions. First, I will presume that this alveolar rhabdo is FOXO1-fusion positive. If not, I would treat as I would an embryonal (fusion negative) rhabdo with vinorelbine/PO cyclophosphamide, vinorelbine/cyclo/temsirolimus, vincristine/irinotecan +/- temozolomide, c...

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