What is your treatment approach in patients with early breast cancer with axillary soft tissue involvement, with or without concurrent lymph node involvement?  

We are fortunate that Mass General has recently published an excellent paper on this topic that helps give guidance (Naoum et al., PMID 37967296). As expected, axillary soft tissue involvement is a high-risk feature, and these patients are at high risk for metastatic disease. For example, if there i...

Thank you for your kind comment Dr. @VanDeusen … I would like to add few points in terms of local therapies that we found during this analysis: The role of a separate nodal radiation field (RLNR) in the setting of ECE or AXT is not well defined, we found that RLNR improved tumor outcomes a...