What is your treatment approach to a young woman with widely metastatic low grade endometrial stromal sarcoma not amenable to complete cytoreduction?
Would you consider "neoadjuvant" hormonal therapy to shrink tumors and potentially make more amenable to complete cytoreduction at a later date?
Would you at least remove the ovaries?
Answer from: Medical Oncologist at Academic Institution
Widely metastatic low-grade ESS in a young woman is quite rare - would suggest pathology confirmation as a first step along with cytogenics/to evaluate for diagnostic fusions in this entity.
Is the pattern in the abdm/pelvis? Or are there lung or other mets as well?
The most effective approach/gui...
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