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What is your treatment approach to patients with confluent actinic keratoses on lower extremities?

Does topical 5FU cause eruptive keratoacanthomas or have any other concerning side effects?
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What therapies do you most commonly use to treat patients with confluent actinic keratoses on the extremities? Select all that apply.

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2 Answers
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Dermatology · UNC Health
Answered on

I find these patients can be very challenging to treat. It is difficult to completely clear the AKs and even if there is success initially, these patients will often develop new adjacent lesions or recurrent lesions within a short time. Nonetheless, we have used various approaches to treating these ...

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Dermatology · Modern Dermatology, Inc.
Answered on

For these field cancerization patients, I definitely appreciate and agree with Dr. @Dr. First Last's thorough answer.

I like to separate the treatment areas into different zones and tackle them over various stages or visits.

I also like to have patients start acitretin 25mg 2 or 3 times a week (appr...

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