I find these patients can be very challenging to treat. It is difficult to completely clear the AKs and even if there is success initially, these patients will often develop new adjacent lesions or recurrent lesions within a short time. Nonetheless, we have used various approaches to treating these ...

For these field cancerization patients, I definitely appreciate and agree with Dr. @Jolly's thorough answer. I like to separate the treatment areas into different zones and tackle them over various stages or visits. I also like to have patients start acitretin 25mg 2 or 3 times a week (approximate...