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What is your treatment method for a patient with drug-resistant focal epilespy that arises from both temporal lobes but already has an anterior temporal lobectomy?

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How do you treat intractable epilepsy secondary to mesial temporal scleorsis?

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2 Answers
Mednet MemberInvited Expert
Neurosurgery · Oregon Health & Science University
Answered on

If the epileptogenic focus is clearly mesial temporal, by EEG, interictal SPECT, neuropsych, and imaging, I would wonder if the amygdala/hippocampus has been adequately resected. If not I would remove these with hippocampal resection ~ 2.5 cm from the anterior hippocampal margin. This should produce...

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Mednet MemberInvited Expert
Neurosurgery · Brigham and Women's Hospital
Answered on

Depending on the location of seizure onset in the remaining temporal lobe, we would generally recommend RNS with a depth electrode traversing the medial structures and a strip electrode over the lateral temporal neocortex.

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