What is your treatment paradigm for rectal cancer in the setting of COVID-19?

We haven't changed our standard recommendation: short course radiation -> 3-4 months of FOLFOX. In a very timely manner, the RAPIDO ASCO abstract was released here in May. It showed that the patients who received short course radiation -> FOLFOX had improved pCR, less disease related treatment failu...

This is a difficult scenario where none of us has enough information to make a completely informed decision. However, all of the modeling that I've seen suggests that personal contact and exposure are the primary drivers of the pandemic. To that end, we've tried to minimize this as much as possible....

Discuss every case in MDC and favor neoadjuvant chemo and short course RT unless concern about circumferential margin, low lying lesion with plan to possible assess for non surgical approach or side wall nodes.

I've been offering and administering short course more routinely but have noted that patients have significant radiation proctitis (tenesmus, frequency, sometimes bleeding) for at least 2-3 weeks post treatment, if not longer.

Other than Imodium and low residue diet, do you recommend additional ther...