Topics:
Rheumatology • Systemic lupus erythematosus • Neurology • Neuro-immunology • Neuropsychiatric Lupus
What is your workup for CSF studies when evaluating for possible CNS Lupus?
In addition, what formula do you use to calculate the IgG index?
Answer from: at Community Practice
CSF studies for CNS lupus are most important in ruling out non-lupus CNS problems, e.g. infections and malignancy. So you want to target CSF studies toward the differential diagnosis of the presenting CNS phenotype. Typically these would include cell counts with diff, glucose, total protein, CSF IgG...
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Answer from: at Academic Institution
There is nothing specific for CNS Lupus, that I know of. Everything in neuroimmunology, for the most part, is EXCLUSION of other diseases. There is NO ACID test!
In neurosarcoidosis, for example, you send off ACE levels in the CSF. But for lupus, there is no such test/entity.
Comments
at Yale University School of Medicine
In addition to the above, I always send serum AQP4...
In addition to the above, I always send serum AQP4...
at Portsmouth Naval Medical Center
@John Peters, MD Agreed. Thank you for the helpful...
@John Peters, MD Agreed. Thank you for the helpful...
at Duke University Medical Center
While not specific to cerebritis, elevated oligocl...
While not specific to cerebritis, elevated oligocl...