What is your workup for CSF studies when evaluating for possible CNS Lupus?

CSF studies for CNS lupus are most important in ruling out non-lupus CNS problems, e.g. infections and malignancy. So you want to target CSF studies toward the differential diagnosis of the presenting CNS phenotype. Typically these would include cell counts with diff, glucose, total protein, CSF IgG...

There is nothing specific for CNS Lupus, that I know of. Everything in neuroimmunology, for the most part, is EXCLUSION of other diseases. There is NO ACID test!

In neurosarcoidosis, for example, you send off ACE levels in the CSF. But for lupus, there is no such test/entity.