I never prescribe nasal sprays for the abortive treatment of migraine because I am not convinced that any of them are more effective than the corresponding tablets (sumatriptan and zolmitriptan) or similar medications in tablet form (gepants). I have extensive experience with the liquid dihydroergo...

Major reasons to consider are: Faster onset of action. Patients with significant nausea/vomiting who cannot tolerate oral. Patients with gastroparesis (due to migraine or other causes) lead to poor absorption of oral medications.

I completely agree with the reasons posted by Dr. @Robblee. I usually agree with my longtime friend, Dr. @Spierings; but I have to say that I disagree with him this time. Certain nasal sprays work more quickly than comparable tablets, such as Zomig nasal spray, which was my favorite way of using a ...