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What medications are preferred and contraindicated for insomnia in patients with a recent stroke or traumatic brain injury?

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Mednet Member
Mednet Member
Psychiatry · McLean Hospital/Harvard Medical School

In acute brain injury (ABI), which includes stroke and traumatic brain injury the focus is often on neurorehabilitation.

The presumption here is that the patient is medically and neurologically stable. For example, not having a stroke in evolution, uncontrolled gastrointestinal bleeding, or similar....

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Mednet Member
Mednet Member
Neurology · University of Virginia, School of Medicine

There are no clinical trials or level I evidence about insomnia management in stroke patients to delineate which medications are off the bat contraindicated. Data is variable on it- some based on mouse models, based on GABAergic medications. That said, the incidence of new-onset insomnia post stroke...

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What medications are preferred and contraindicated for insomnia in patients with a recent stroke or traumatic brain injury? | Mednet