What neoadjuvant chemotherapy do you suggest for a rapidly growing triple-negative breast cancer?
Would you give pembrolizumab with chemotherapy or just chemotherapy? The patient had a history of mantle radiation several years ago.
Answer from: Medical Oncologist at Academic Institution
If the patient has non-metastatic, operable triple-negative breast cancer that is at least 2 cm in diameter or positive for axillary lymph node metastases, I would use the KEYNOTE-522 regimen (1 year of pembrolizumab in combination with 4 cycles of neo-adjuvant paclitaxel, carboplatin followed by 4 ...
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Medical Oncologist at Duke University Medical Center KEYNOTE-522 is the state-of-the-art treatment for ...
Medical Oncologist at Los Angeles VA Medical Center Dr. @Robert Wesolowski and Dr. @Gretchen G. Kimmic...
Answer from: Medical Oncologist at Academic Institution
As with any rapidly growing cancer, we employ the most effective treatment in a timely manner. In the case of a localized triple-negative breast cancer (TNBC), effective systemic neoadjuvant therapy is indicated. The start of systemic neoadjuvant therapy needs to follow three essential steps:
Confi...
KEYNOTE-522 is the state-of-the-art treatment for ...
Dr. @Robert Wesolowski and Dr. @Gretchen G. Kimmic...