What neoadjuvant regimen would you consider using for a healthy patient with node positive TNBC who is refusing anthracycline?
Answer from: Medical Oncologist at Academic Institution
In a patient with node-positive TNBC not eligible for an anthracycline, or refusing an anthracycline, I would strongly consider proceeding with a platinum + taxane + pembrolizumab, mirroring the NeoPACT trial presented by @Priyanka Sharma at ASCO 2022, which is the same regimen of carboplatin/doceta...
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Answer from: Medical Oncologist at Academic Institution
For node positive TNBC patients who are not eligible for anthracycline, or who refuse anthracycline, I would use 6 cycles of TC per the West German Plan B trial (Nitz et al., PMID 30785826). This study randomized patients with high-risk localized breast cancer to epirubicin/cyclophosphamide x 4 foll...
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Medical Oncologist at Providence Hospital and Medical Centers
Dr. @Buys, Would you consider the NeoSTOP trial (...
Dr. @Buys, Would you consider the NeoSTOP trial (...
Medical Oncologist at Breastlink Medical Group
This (carbo + doce) is my preferred neo adjuvant n...
This (carbo + doce) is my preferred neo adjuvant n...
Medical Oncologist at University of Utah Huntsman Cancer Institute
Yes, this is certainly a reasonable regimen.
Yes, this is certainly a reasonable regimen.
Medical Oncologist at NYU Winthrop Hospital
Weekley Carbo/Taxol with Pembrolizumab
Weekley Carbo/Taxol with Pembrolizumab