What parameters would you use to decide whether to stop hydroxychloroquine in a patient whose lupus is well controlled but is found to have a prolonged QT interval on routine EKG?

This is an excellent question for which there is no one-size-fits-all answer. The first question is how prolonged the QT is, and if there is another drug they are on that is contributing to the prolonged QT. Obviously, it is important to avoid prescribing other medications that prolong the QT. It is...

This scenario requires a discussion with the patient involving shared decision-making.

On the one hand, the numerous benefits of taking HCQ in SLE are numerous (fewer CV events, less DMII, fewer infections and cancers, increased remission rates, reduced SLE flares, and it is the only drug proven to p...

Great comments by Dr. @Dr. First Last & Dr. @Dr. First Last! As alluded to by Dr. @Dr. First Last, I think a lot of the concern re QTc prolongation with hydroxychloroquine came after it was studied in COVID-19 patients at much higher dosages than we use in Rheumatology. For example, the RECOVERY tri...