What risk factors would favor the addition of ovarian function suppression to endocrine therapy in triple-positive breast cancer?
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Which pre-menopausal female patient with HR+ HER2+ patients would you give OFS alongside endocrine therapy?
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1 Answer
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Medical Oncology · OHSU, Knight Cancer Institute
Answered on · Updated on
Young age less than 40, node positive, high-grade, bulky tumor, or any patient at high risk of recurrence (requiring chemo) or residual tumor, I would favor giving ovarian suppression as per the SOFT and TEXT trial.
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