What RT margins do you use when treating Grade III anaplastic gliomas?

At the Cleveland Clinic, we extrapolate from the GBM literature and from the Cairncross RTOG 9402 and Van den Bent EORTC trials showing the benefit of chemotherapy, and thus deliver radiation with concurrent temozolomide. We typically treat to 5940 cGy in 33 fractions. We treat PTV1 to 5040 cGy and ...