What strategies do you find helpful to stop zolpidem in patients who have been taking the medicine for months or years?
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Have you used orexin-receptor antagonists such as lemborexant to help patients taper off zolpidem?
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1 Answer
Mednet Member
Psychiatry · University of Miami Miller School of Medicine/ Jackson Memorial Hospital - Jackson Health System
Answered on
Zolpidem has significant withdrawal, and if not careful, the patient will perceive it as a need for zolpidem for sleep. Technically, it is not working after about 6-8 months due to the accommodation of receptors. Please use lemborexant hintly for 1 week, reduce to 2.5 mg zolpidem for 1 month, and th...
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