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What strategies do you use for large breasted women receiving whole breast radiation?

Particularly for patients too large for prone breast treatment, do you use a breast immobilization device or bra? Do you change your fractionation? Would you consider coming off the whole breast and treating the involved breast segment or enlarged boost area? Does your skin care regimen differ for larger obese women compared to non-obese (for example, use of oral or topical antibiotics or avoiding emollients)?
3 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

If we can't do prone, we use a styroform wedge in the inframammary region to decrease the breast fold and thus, decrease the inferior margin and amount of inframammary fold we have to treat. I would initially try hypofractionation with mixed beam with a field-in-field technique and if the dose homog...

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Radiation Oncology · Allegheny Health Network, Pittsburgh
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One other comment I would make is we too routinely assume a patient needs whole breast irradiation. For larger breasted women with T1-2 (< 3 cm) N0 tumors partial breast irradiation with 40 Gy/15 fractions (IMPORT LOW) or 30 Gy/5 fractions (Livi et al., PMID 25605582) can be considered to reduce dos...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

We have two options to reduce volume and thus morbidity. One is to import low-volume techniques for 26 Gy in 5 fractions or 40 Gy in 15 fractions, based on dose homogeneity, or APBI 30 Gy in 5 fractions. Selection can be based on pathology and the technology available.

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