What systemic therapy do you recommend for a patient with a local relapse of ewing sarcoma who previously received VDC-IE?

With great respect, this is a question that should neither be asked nor answered in this forum. Recurrent Ewing sarcoma is a complex subject. While the prognosis is poor, it is not monolithically poor. There are a host of factors which influence the choice of therapy for a patient with recurrent Ewi...

Irinotecan/temozolomide.