What systemic therapy would you offer a postmenopausal women with oligometastatic sternal disease which developed while on tamoxifen?
Provided the sternal lesion was low volume and treated with curative intent and patient has been on tamoxifen for < 5 years, would you switch to AI or move on to AI+CDK 4/6 inhibitor?
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Would you use AI alone or AI plus CDK4/6 inhibitor ?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · Penn Medicine, University of Pennsylvania Health System
Answered on
For an isolated sternal metastasis, I would normally refer to radiation oncology for focused radiation, and I would change her hormonal therapy to an aromatase inhibitor, as these patients can have very long survival times. Some patients survive longer than a decade. (Milano MT et al).
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