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What therapies do you most commonly recommend for prevention of NMSC in organ transplant patients?

What patients are good candidates for acitretin? When do you prescribe acitretin for chemoprophylaxis in patients with multiple NMSC?
1 Answer
Mednet MemberInvited Expert
Dermatology · Florida State University College of Medicine
Answered on · Updated on

First and foremost, we assess transplant patients and circle, number, and label all their skin cancers so we can catalogue them.

We then prioritize their skin cancers in order to remove them in order of "worst first".

We immediately start field therapy with calcipitrione and 5-FU twice a day for a week on facial areas and 10 days elsewhere.

If they are allergic to 5-FU, we will do overnight PDT with a Jessner-like prep and often Fraxel CO2.

If there are multiple SCCs and SCCis, typically on scalp or any area, we will often biopsy all of them and look at the biopsy in real time. We then tattoo the cancers sites with India ink at 3, 6, 9 and 12 o'clock and then use C 5FU to area a week later, then wait 6 weeks and select and excise several of...

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