What therapy would you recommend for metastatic myxoid liposarcoma in a young patient with anthracycline cardiomyopathy with EF 25% who failed eribulin?
Would you even consider trabectedin in this case given its cardiotoxicity?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · Emory University
Answered on
I am going to guess that:
1. Patient has doxorubicin cardiomyopathy because she got adjuvant doxorubicin and ifosfamide with initial tumor.
2. It was long enough ago that there has been time to develop cardiomyopathy.
3. If she was without progression long enough to develop cardiomyopathy you could make a case that adjuvant chemo did some good and if you do something like that again you might get another long DFS.
4. You could go back to ifosfamide as a single agent. In myxoid/round cell I think the...
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