What topical and oral therapies do you prescribe for patients with recalcitrant melasma?
1 Answer
Mednet Member
Dermatology · Forefront Dermatology
Answered on
This is my Melasma algorithm:
- Hydroquinone triple cream qhs x 6 months + azelaic acid in the AM + tinted sunscreen
- Consider PO TXA (half of 650 mg tab bid), polypodium leucotomos bid (heliocare)
- Maintenance: stop hydroquinone and switch to compounded TXA/kojic/tretinoin combo cream qhs + vitamin C/azelaic in the morning
- Cysteamine cream a few times weekly at bedtime
- Add on microneedling to topicals before higher-risk things (peels, lasers)
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