What treatment would you consider for metastatic urachal carcinoma following progression on FOLFOX and FOLFIRI?
Molecular profiling revealed no targetable alterations, however tumor mutational burden was >10 mut/Mb.
1 Answer
Mednet MemberInvited Expert
Medical Oncology · AdventHealth Cancer Institute
Answered on
Metastatic urachal adenocarcinoma is a challenging disease to treat with significant unmet needs. Initial therapy replicates therapy for metastatic colorectal adenocarcinoma and may include FOLFOX, FOLFIRI or FOLFOXIRI potentially combined with bevacizumab. Salvage therapy may include 1) trials (gui...
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