What treatment would you give to a pediatric patient with rhabdomyosarcoma in first relapse?

Typically it depends on the previous treatment of the patient’s primary RMS in terms of my approach to relapse RMS. In general, many would go with treatment per ARST0921 with vinorelbine, cyclophosphamide, and Temsirolimus, with the caveat that it may be different depending on previous drug exposure...