What would be your approach in a patient with MET amplification and PDL-1 80% expression?

Need to clarify whether it is very high amplification ( need to verify with NGS provider). If high, can consider off-label Crizotinib ( these tend to metastasize to brain more frequently. Else, can start chemoimmunotherapy and switch to Crizo on progression , or one of the newer agents if approved b...