What would be your approach in a patient with MET amplification and PDL-1 80% expression?
Do you use crizotinib for first-line therapy?
Answer from: Medical Oncologist at Community Practice
Need to clarify whether it is very high amplification ( need to verify with NGS provider). If high, can consider off-label Crizotinib ( these tend to metastasize to brain more frequently. Else, can start chemoimmunotherapy and switch to Crizo on progression , or one of the newer agents if approved b...
Comments
Medical Oncologist at Kettering Cancer Center Will look into amplification strength, thank you. ...
Medical Oncologist at Cancer Care Specialists/Renown Oncology/UNR Not much data, In the Immunotarget global data, me...
Will look into amplification strength, thank you. ...
Not much data, In the Immunotarget global data, me...