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What would be your choice of endocrine therapy for a patient with HR+ early stage second breast primary after completing 5 years of adjuvant AI?

The patient has been off her AI for two years.
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Would you use the same aromatase inhibtor for a patient who develops a second HR+/HER2- primary breast cancer 2 years after completing 5 years of adjuvant AI?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Ohio State University
Answered on

There are no studies to provide guidance in this situation as far as I am aware as most adjuvant studies excluded patients with prior history of breast cancer. Given that the second primary breast cancer was discovered 2 years after completion of adjuvant aromatase inhibitor, it probably developed a...

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