What would be your recommended regimen for an AYA patient with relapsed mediastinal pure seminoma, with relapse 20 months after completion of BEP?
Relapse 20 months after completion of BEP x 3; biopsy confirmed pure seminoma, normal bHCG and AFP, no disease outside of mediastinum.
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What would be your recommended regimen for an AYA patient with relapsed mediastinal pure seminoma, with relapse 20 months after completion of BEP?
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1 Answer
Mednet Member
Medical Oncology · IHA Hem Onc Consult
Answered on
Mediastinal seminoma is rare and has a high cure rate with chemotherapy alone (BEP x3). I would refer a patient like this to a high-volume center. Treatment options are high-dose chemotherapy followed by ASCT vs. resection. This should be a tumor board discussion. Despite limited data and the interv...
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