What would you offer to a patient with musculoskeletal pain from tarlatamab, requiring hospitalization and opioid use?

Bone and muscle pain with tarlatamab can be significant (affecting nearly one-third of patients in clinical trials, I think). A multimodal plan combining opioids with non-opioid analgesics, supportive therapies, and proactive side effect monitoring is often necessary to combat this.

The pathway that ...