What would you offer to a patient with musculoskeletal pain from tarlatamab, requiring hospitalization and opioid use?
The patient is refractory to steroids. Any preferred DMARDs?
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For steroid-refractory musculoskeletal toxicity from tarlatamab, what is your preferred next-line option?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
Answered on
Bone and muscle pain with tarlatamab can be significant (affecting nearly one-third of patients in clinical trials, I think). A multimodal plan combining opioids with non-opioid analgesics, supportive therapies, and proactive side effect monitoring is often necessary to combat this.
The pathway that ...
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