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What's your follow-up protocol for a near complete response (nCR) in rectal patients considering non-operative management (NOM)?
OPRA trial recommends continued NOM if no signs of progression in nCR patients vs. NCCN recommends repeat studies at 8 weeks, and if not converted to clinical CR, then proceed to TME.
Which recommendation do you use, and during your follow-up period, how do you address nodes when assessing response?
Answer from: Radiation Oncologist at Academic Institution
This is a question that comes up in our colorectal tumor board routinely. For patients with a near-complete response after the completion of TNT, we recommend repeating an MRI of the rectum and endoscopic exam ~8 weeks later. If there is still a lack of complete response, our formal recommendation i...
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