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What dose of methotrexate do you typically continue to prevent antibody formation when adding infliximab for sarcoidosis?

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What dose of methotrexate do you typically continue to prevent antibody formation when adding infliximab for sarcoidosis?

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Pulmonology · Thomas Jefferson University Hospitals
Answered on

Infliximab is a chimeric molecule that contains approximately 25% murine protein, so it can be immunogenic in some individuals.

Development of anti-infliximab antibodies (ATI) has been reported in various autoimmune diseases treated with infliximab.

Around 10 to 50% of individuals with rheumatoid arth...

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