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When and how do you deviate from efgartigimod (Vyvgart) dosing from the drug label recommendation of weekly infusions for four weeks in patients with myasthenia gravis?

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What have you found to be the most reliable schedule for efgartigimod in patients with myasthenia gravis?

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1 Answer
Mednet Member
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Neurology · University of Minnesota
Answered on

In the landmark ADAPT study, efgartigimod vs placebo was given in patients with MG initially as weekly infusions x4. The timing of the second and subsequent cycles was determined on a case-by-case basis, based on the patient's clinical response and serial measurement of quantitative MG parameters (M...

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