When and how do you perform genetic testing for congenital myasthenia gravis in seronegative cases?
Do you generally wait to see if they have response to immunotherapy first?
What type of genetic testing do you send?
Related discussion on theMednet on seronegative MG
1 Answer
Mednet MemberInvited Expert
Neurology · Northwestern Medicine
Answered on
I believe that these congenital myasthenic syndromes can start at birth or early childhood, as we are all familiar with muscular weakness, particularly extraocular muscles, and bulbar, which is fatigable, worsening with physical activity, and there > 30 genes responsible, and symptoms vary by the Ge...
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