When are steroids indicated in the treatment of strep pneumo meningitis?

Yes, I recommend a four-day regimen of dexamethasone 0.4-0.6 mg per kilogram daily given before or with the first dose of antibiotics. Delaying the administration of corticosteroids would reduce the desired anti-inflammatory effects.

1. van de Beek et al., PMID 14998499

2. Brouwer et al., PMID 26362566...