When discontinuing Denosumab after more than 2-3 years of therapy, when do you recommend giving the first dose of zoledronic acid?
3 Answers
Mednet MemberInvited Expert
Endocrinology · Duke University Hospital
Answered on
My practice has been that after 2-3 years of denosumab, I wait 6 months and then start zoledronic acid.
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Mednet Member
Endocrinology · Providence John Wayne Cancer Institute Endocrinology
Answered on
Six months after the last injection.
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Mednet Member
Rheumatology · Sunshine Rheumatology & Arthritis Center
Answered on
Yes, 6 months after last Prolia shot. I give 2 doses of Zoledronic 1 year apart and then consider drug holiday based on the DEXA report.
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