When do you consider a levodopa trial in patients with new-onset dystonia?

Levodopa trials are recommended in all children with any type of dystonia and also adults whose phenotype could be consistent with dopa-responsive dystonia (DRD). An observed levodopa trial (generally up to 300–400 mg of levodopa daily in adults or 4–5 mg/kg/day in children) for at least a month is ...