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When do you consider antipsychotic augmentation of antidepressants for PTSD?

In light of publication from Davis et al., PMID 39693081.
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Psychiatry · Yale School Of Medicine Pitt Lab
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Traditionally, antipsychotic augmentation of antidepressants was reserved for patients with high levels of paranoia or frank psychosis. The VA Cooperative Study of Risperidone also found that antipsychotic augmentation could be helpful for PTSD-related insomnia. The recent brexpiprazole study (Davis...

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