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SpecialtiesHospital MedicineQuestion

When do you consider pharmacologic therapies such as sodium tablets, urea, vaptans, etc., vs conservative management for persistent asymptomatic hyponatremia in hospitalized patients?

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1 Answers
Mednet Member
Mednet Member
Hospital Medicine · Emory University Hospital

For patients with SIADH, I consider active therapy in one of the following scenarios:

  1. Na remains <130, especially <125–128, despite 24–48 h of appropriate conservative management.
  2. Fluid restriction is not feasible (thirst, tube feeds, need for hydration, patient cannot adhere).
  3. The patient has recu...

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