When do you consider testing autoimmune antibodies for axonal polyneuropathies without clear etiology?
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Do you routinely test for axonal neuropathy autoimmune antibody panels in patients with slowly progressive idiopathic axonal sensorimotor neuropathy?
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2 Answers
Mednet MemberInvited Expert
Neurology · University of Minnesota
Answered on
Dr. @Dr. First Last gave an excellent summary of the clinical red flags that should trigger antibody testing in polyneuropathies. I would like to highlight that not all antibodies are pathogenic or cause the same phenotypes/clinical syndromes; therefore, I would like to break it down by antibody gro...
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Mednet MemberInvited Expert
Neurology · Wayne State University School of Medicine
Answered on · Updated on
Testing for autoimmune antibodies in axonal polyneuropathies without a clear etiology is considered when the clinical picture, history, or associated features suggest an underlying immune-mediated or paraneoplastic process. Here’s when it would be reasonable to consider antibody testing:
1. Subacute...
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