When do you consider the use of lumateperone to treat schizophrenia spectrum disorders?

It is obscene that these drugs cost $1,400-$1,800/month retail.

I have tried lumateperone for schizophrenia patients in clinical practice, and so far, I have not seen it to be effective. Placebo may work better than this.

I have found that Caplyta has properties similar to quetiapine for sleep and mood irritability in a bipolar type patient with not as much weight gain insulation. I’ve given it to manic patients and had very little efficacy.

Most of the new medications are not available in the CA state system.