When do you perform a kidney biopsy in a patient with AKI that is thought to be related to an immune checkpoint inhibitor?

I would wait for the response to corticosteroid therapy before the renal biopsy.

The kidney biopsy offers both diagnostic and prognostic information so I personally pursue the renal biopsy unless there is a compelling reason not to (i.e. coagulopathy). Although ATIN is the most common lesion found on renal bx performed for the evaluation of CPI-AKI, other actionable renal diseas...