When do you recommend adjuvant chemotherapy for an incidentally detected, low grade appendiceal mucinous neoplasm s/p appendectomy?
What factors do you consider - perforation, size?
2 Answers
Mednet MemberInvited Expert
Medical Oncology · Mayo Clinic
Answered on
Low-grade appendiceal mucinous neoplasm (LAMN) is one common type of neoplastic mucinous appendiceal lesions and it is a true neoplasm that produces abundant mucin but does not have infiltrative epithelial invasion of the appendiceal wall (pushing but not infiltrating). LAMN can be discovered incide...
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Mednet MemberInvited Expert
Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
Answered on · Updated on
Accurate histologic diagnosis of appendiceal neoplasms can be quite challenging. A complete examination of the entire specimen and rigorous evaluation of the appendiceal wall for any evidence of epithelial invasion is crucial to distinguish between adenocarcinomas and all other types of mucinous les...
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