When do you recommend HLA testing prior to prescribing lamotrigine, carbamazepine, or oxcarbazepine to patients of Asian descent?
Answer from: at Community Practice
I never use carbamazepine given how it’s a pan inducer and often lowers the level of other medications that may be in the regimen, such as quetiapine and haloperidol, since they are mainly metabolized by CYP3A4.
Oxcarbazepine has a 50% reduction in the induction of carbamazepine, so I use tha...