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When do you redose IVIG in GBS patients who were under-treated and are worsening?

Is there any data supporting this?
2 Answers
Mednet Member
Mednet MemberInvited Expert
Neurology · University of Minnesota
Answered on

Based on recently published data from the randomized SID-GBS trial, this approach is not a good idea. A second course of IVIG not only did not clearly benefit patients with GBS with poor prognosis, but it was associated with a significantly higher risk of adverse events including thromboembolism.

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Mednet Member
Mednet Member
Neurology · Piedmont HealthCare
Answered on

PLEX is in my opinion, the way to go with intractable GBS or any type of demyelinating or primarily demyelinating neuropathy that is going through an acute worsening with threatening presentation including bulbar symptoms or signs. This maybe followed by IVIg but only if the patient is out of the cr...

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