When do you stop immunosuppressants in patients with GPA?

It depends on the severity of the initial presenting symptoms and which organs were involved. However, generally, I don't stop all treatments and maintain the patient on at least MTX or azathioprine, potentially for life, even if these were not part of the initial remission-inducing regimen, such as rituximab or cytoxan.

GPA is a potentially deadly condition, and if there was significant organ involvement, or even when not sometimes, the risk of relapse, which is common, is high, and there is no...