When do you suggest ovarian suppression for fertility preservation in premenopausal women receiving neo/adjuvant chemotherapy?

The benefit of ovarian suppression in young breast cancer patients should be looked into from two different aspects. First, the suppression of the ovary resulting in the hormone receptor-dependent cancer stem cell (minimal residual disease) suppression, and second, the preservation of the fertility after the chemotherapy. The second part, the preservation of ovarian function is critical in young women who want to conceive children. There had been several sized retrospective reviews, and original studies for the 'preservation of the fertility in young women who were treated with chemotherapy'.

Many studies that studied ovarian function preservation used different chemotherapy and different outcome measures of the preservation of the fertilit...