When do you use tirofiban for acute ischemic stroke?

Early tirofiban infusion after IV thrombolysis makes sense for acute strokes due to intracranial stenosis. As an endovascular specialist, I have often seen MCA or basilar occlusions reopen with IV thrombolysis but only to reocclude when there is an underlying severe atherosclerotic lesion. My approa...

I agree with the prior post. This study appears to target acute ischemic stroke due to intracranial atherosclerotic disease (ICAD) etiology, where tirofiban (or other antiplatelet infusions) administered post-thrombolytics make mechanistic sense.

ICAD occlusions are "hot lesions", driven by active m...