When eyelid tissue loss is substantial, when is staged reconstruction preferred over primary closure?

Tissue is rarely actually missing, but more often rolled up or difficult to identify. If tissue is truly missing (most often from a dog bite more than any other type of trauma, in my experience), this question would need to be addressed on a case-by-case basis. There are a number of factors to consider, including:

1. Mechanism of injury and infection risk (e.g., organic material/debris)
2. Patient age and amblyopia risk (e.g., Hughes or Cutler beard are less optimal in a patient of amblyogenic age)
3. R...