When (if ever) would you offer radiotherapy for renal cell carcinoma following nephrectomy?  

There is no indication for any type of radiation after nephrectomy in resected RCC. Often a 'positive' renal vein margin is not a true positive, but rather an artifact of having a renal vein thrombus and this should be discuss with the Urologist and Pathologist and clarified in the report. Having sa...

I have not personally offered radiation in this setting.A PS-weighted multi-institutional study (excluding patients with neoadjuvant therapy or non-vascular margin positivity) found that positive vascular margins are associated with an increased risk of local recurrence with no difference in distant...