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When is a lumbar puncture indicated in a lymphoma staging work up for a pediatric or AYA patient?

Is an LP only recommended in the setting of particular subtypes of lymphoma or symptoms of CNS disease?
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In which types of pediatric lymphoma do you perform a diagnostic LP?

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1 Answer
Mednet Member
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Pediatric Hematology/Oncology · University of Toronto
Answered on
LP is not necessary in any Hodgkin patient irrespective of stage.
LP plus IT chemo is indicated in all advanced stage NHL. The one exception to that is primary mediastinal B-cell with sclerosis which is an intermediate grade lymphoma (similar to Hodgkin) and rarely spreads to CNS.
It is true that ...

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